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The science behind Revalor®-XS

Proprietary delayed-release technology delivers trenbolone acetate and estradiol in a unique way.

Revalor XS

Designed for steers fed in confinement, Revalor®-XS delivers the
combination of trenbolone acetate and estradiol of two-implant programs in a single administration, thanks to its unique, delayed­ release technology.

Each Revalor®-XS implant consists of 10 small pellets.

  • The first four pellets are uncoated, which allows them to go to work immediately after implanting.
     
  • The other six pellets are coated with the patented X7™ polymer. The delayed-release pellets take effect after 70 to 80 days on feed, providing the performance of a terminal implant without the need for reprocessing.
Revalor XH
End section - Uncoated (25x)
  Revalor XH
End section - Coated (25x)

 

Miroscopic view of coated and uncoated pellets

Each pellet contains 20 mg of trenbolone acetate and 4 mg of estradiol, for a total dose of 200 mg of trenbolone acetate and 40 mg of estradiol per implant.

 

Trenbolone acetate blood levels

Revalor XS

Pharmacokinetic study

The following study compares the blood levels of trenbolone acetate and estradiol for two different treatments: Revalor®-XS and a comparable-dose, two-implant program.*


PROTOCOL
  • The study involved 20 animals. Ten animals were implanted with Revalor®-XS, while the remaining ten were assigned to the two-implant program group.
     
  • Both groups were implanted on Day 0. The two-implant program group was implanted again on Day 70.
     
  • Blood levels of trenbolone acetate and estradiol were measured twice per week for 200 days.

CONCLUSIONS

Revalor®-XS delivered more consistent levels of trenbolone acetate throughout the course of the study.

* Two-implant program:

  • Composition of 1st implant = 80 mg trenbolone acetate and 16 mg estradiol
  • Composition of 2nd implant = 120 mg trenbolone acetate and 24 mg estradiol (Revalor®-S)

† Data on file.
REVALOR® is a registered trademark of Intervet International B.V. Used under license.